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Ching-Chi Chiu, Tu-Hsueh Yeh, Chin-Song Lu, Yin-Cheng Huang, Yi-Chuan Cheng, Ying-Zu Huang, Yi-Hsin Weng, Yu-Chuan Liu, Szu-Chia Lai, Ying-Ling Chen, Yu-Jie Chen, Chao-Lang Chen, Hsin-Yi Chen, Yan-Wei Lin, Hung-Li Wang*. (2017) PARK14 PLA2G6 mutants are defective in preventing rotenone-induced mitochondrial dysfunction, ROS generation and activation of mitochondrial apoptotic pathway. Oncotarget. 8:79046-79060.

C-Y Chen, Y-H Weng, K-Y Chien, K-J Lin, T-H Yeh, Y-P Cheng, C-S Lu, and H-L Wang* (2012) (G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD. Cell Death and Differentiation 19, 1623–1633

Chu Lan Lao, Chin-Song Lu, Jin-Chung Chen* (2013) Dopamine D3 receptor activation promotes neural stem / progenitor cell proliferation through AKT and ERK1/2 pathways and expands type-B and type–C cells in adult subventricular zone. Glia 61(4), 475-489.

Jyh-Jeen Yang, Ruo-Ciao Cheng, Pi-Cheng Cheng, Yi-Chi Wang, and Rong-Chi Huang*. (2017) KATP channels mediate differential metabolic responses to glucose shortage of the dorsomedial and ventrolateral oscillators in the central clock. Scientific Reports. 7(1): 640.

Chuen-Mao Yang, Chih-Chung Lin, Hsi-Lung Hsieh*. (2017) High-Glucose-Derived Oxidative Stress-Dependent Heme Oxygenase-1 Expression from Astrocytes Contributes to the Neuronal Apoptosis. Molecular Neurobiology, 54(1): 470-483.

Cheng-Yu Tsai, Ching-Yen Tsai, Sebastian J. Arnold and Guo-Jen Huang*. (2015) Ablation of hippocampal neurogenesis in mice impairs the response to stress during the dark cycle. Nature Communications. 6: 8373.

Ing-Tsung Hsiao, Yi-Hsin Weng, Chia-Ju Hsieh, Wey-Yil Lin, Shiaw-Pyng Wey, Mei-Ping Kung, Tzu-Chen Yen, Chin-Song Lu and Kun-Ju Lin*. (2014) Correlation of Parkinson Disease Severity and 18F-DTBZ Positron Emission Tomography. JAMA Neurology, 71(6): 758-66.

S.F. H. Waqas, A.C. Hoang, Y.-T. Lin, G. Ampem, A. Hind, L. Balogh, J.C. Chen, I. Gerling, J.-S. Lim, S. Nam, J. Martinez-Ibanez, S. Paschke, J. Real, R. Quillet, S. Ayachi, S. Frederic, M. Schneider, C. Seroogy , J. Thuroczy, T. Röszer (2017) Neuropeptide-FF increases M2 activation and self-renewal of adipose tissue macrophages. Journal of Clinical Investigation, JCI90152.

Y.T. Lin and J.C. Chen (2011) The involvement of dorsal root ganglia BDNF-TrkB in inflammatory pain in vivo and in vitro, Journal of Neuroinflammation, 8:126-147.

C.C. Lin, H.L. Hsieh, R.H. Shih, P.L. Chi, S.E. Cheng, J.C. Chen* and C.M. Yang* (2012) NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin- induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes, Cell Communication and Signaling, 10:35. (*, co-coresponding).

Luo, S.F., Y.Y. Fang, H.L. Hsieh, P.L. Chi, C.C. Lin, L.D. Hsiao, C.C. Wu, J.S. Wang, and C.M. Yang.* (2010) Involvement of MAPKs and NF-kB in TNF-a-induced VCAM-1 expression in human rheumatoid arthritis synovial fibroblasts. Arthritis & Rheumatism, 62:105-116.

Chi, P.L., Y.W. Chen, L.D. Hsiao, Y.L. Chen, and C.M. Yang.* (2012) Heme oxygenase-1 attenuates IL-1b-induced cPLA2 expression via a decrease in NADPH oxidase/ROS/AP-1 activation in human rheumatoid arthritis synovial fibroblasts. Arthritis & Rheumatism, 64:2114-2125.

Weng YH, Chen CY, Lin KJ, Chen YL, Yeh TH, Hsiao IT, Chen IJ, Lu CS, Wang HL* (2016)  (R1441C) LRRK2 induces the degeneration of SN dopaminergic neurons and alters the expression of genes regulating neuronal survival in a transgenic mouse model. Experimental Neurology, 275, 104-115.

Chou JS, Chen CY, Chen YL, Weng YH, Yeh TH, Lu CS, Chang YM, Wang HL* (2014) (G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse. Neurobiology of Disease, 68, 190-199.

Cai N, Li Y, Chang S, Liang J, Lin C, Zhang X, Liang L, Hu J, Chan W, Kendler KS, Malinauskas T, Huang GJ, Li Q, Mott R, Flint J. (2015) Genetic control over mtDNA and Its relationship to major depressive disorder. Current Biology 21;25(24):3170-77.

Huang GJ*, Bannerman D, Flint J. (2008) Chronic fluoxetine treatment alters behaviour, but not adult hippocampal neurogenesis, in BALB/cJ mice. Molecular Psychiatry 13, 119-121.

Chih-Chung Lin, His-Lung Hsieh, Pei-Ling Chi, Chien-Chung Yang, Li-Der Hsiao, Chuen-Mao Yang*. (2014) Up-regulation of COX-2/PGE2 by ET-1 mediated through Ca2+-dependent signals in mouse brain microvascular endothelial cells, Molecular Neurobiology, 49, 1256-1269.

Chih-Chung Lin, His-Lung Hsieh, Pei-Ling Chi, Chien-Chung Yang, Li-Der Hsiao, Chuen-Mao Yang*. (2014) Up-regulation of COX-2/PGE2 by ET-1 mediated through Ca2+-dependent signals in mouse brain microvascular endothelial cells, Molecular Neurobiology, 49, 1256-1269.

Tu-Hsueh Yeh, Szu-Chia Lai, Yi-Hsin Weng, Hung-Chou Kuo, Yah-Huei Wu-Chou, Chia-Ling Huang, Rou-Shayn Chen, Hsiu-Chen Chang, Bryan Traynor, Chin-Song Lu*. (2013) Screening for C9orf72 repeat expansions in parkinsonian syndromes. Neurobiol Aging, 34(4), 1311e3-e4.

Chou AH, Chen SY, Yeh TH, Weng YH, Wang HL* (2011) HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3. Neurobiology of Disease, 41, 481-488.

Chen YW, Chen IJ, Wang JS*. Absolute hypoxic exercise training increases thrombin generation by enhancing procoagulant platelet-derived microparticles under high shear flow in sedentary men. Clin Sci (Lond). 2013 May;124(10):639-49.

Fu TC, Wang CH, Lin PS, Hsu CC, Cherng WJ, Huang SC, Liu MH, Chiang CL, Wang JS*. Aerobic interval training improves oxygen uptake efficiency by enhancing cerebral and muscular hemodynamics in patients with heart failure. Int J Cardiol. 2013 Jul 15;167(1):41-50.

Wang JS*, Fu TC, Wang CH, Chou SL, Liu MH, Cherng WJ. Exertional periodic breathing potentiates erythrocyte rheological dysfunction by elevating pro-inflammatory status in patients with anemic heart failure. Int J Cardiol.2013 Aug 20;167(4):1289-97.

Wang JS*. Anemia, heart failure and exercise training. Int J Cardiol. 2013 Sep 30;168(2):1525-6.

Wang JS*, Fu TC, Lien HY, Wang CH, Hsu CC, Wu WC, Chien YW, Cherng WJ. Effect of aerobic interval training on erythrocyte rheological and hemodynamic functions in heart failure patients with anemia. Int J Cardiol. 2013 Sep 30;168(2):1243-50.

Chen YW, Chen YC, Fu TC, Wang CH, Huang SC, Wang JS*. Anemic comorbidity reduces capacity of endogenous thrombin generation and is associated with consumptive coagulopathy in patients with heart failure. Int J Cardiol. 2013 Oct 12;168(5):4965-7.

Weng TP, Huang SC, Chuang YF, Wang JS*. Effects of interval and continuous exercise training on CD4 lymphocyte apoptotic and autophagic responses to hypoxic stress in sedentary men. PLoS One. 2013 Nov 13;8(11):e80248.

Weng TP, Fu TC, Wang CH, Hsu CC, Wang JS*. Activation of lymphocyte autophagy/apoptosis reflects haemodynamic inefficiency and functional aerobic impairment in patients with heart failure. Clin Sci (Lond). 2014 Nov;127(10):589-602.

Wang JS*, Lee MY, Lien HY, Weng TP. Hypoxic exercise training improves cardiac/muscular hemodynamics and is associated with modulated circulating progenitor cells in sedentary men. Int J Cardiol. 2014 Jan 1;170(3):315-23.

Chen YC, Ho CW, Tsai HH, Wang JS*. Interval and continuous exercise regimens suppress neutrophil-derived microparticle formation and neutrophil-promoted thrombin generation under hypoxic stress. Clin Sci (Lond). 2015 Apr;128(7):425-36.

Wang JS*, Chang YL, Chen YC, Tsai HH, Fu TC. Effects of normoxic and hypoxic exercise regimens on monocyte-mediated thrombin generation in sedentary men. Clin Sci (Lond). 2015 Aug 1;129(4):363-74.

Huang SC, Wong MK, Lin PJ, Tsai FC, Wen MS, Kuo CT, Hsu CC, Wang JS*. Passive Leg Raising Correlates with Future Exercise Capacity after Coronary Revascularization. PLoS One. 2015 Sep 11;10(9):e0137846.

Chou SL, Huang YC, Fu TC, Hsu CC, Wang JS*. Cycling exercise training alleviates hypoxia-impaired erythrocyte rheology. Med Sci Sports Exerc. 2016 Jan;48(1):57-65.

Huang CH, Hsu CC, Chen CP, Chow SE, Wang JS, Shyu YC, Lu MJ. Negative pressure induces p120-catenin-dependent adherence junction disassembly in keratinocytes during wound healing. Biochim Biophys Acta. 2016 Sep;1863(9): 2212-20.

Tsai HH, Chang SC, Chou CH, Weng TP, Hsu CC, Wang JS*. Exercise Training Alleviates Hypoxia-induced Mitochondrial Dysfunction in the Lymphocytes of Sedentary Males. Sci Rep. 2016 Oct 12;6:35170.

Huang SC, Wong MK, Lin PJ, Tsai FC, Chu JJ, Wu MY, Fu TC, Wang JS*. Short-term intensive training attenuates the exercise-induced interaction of mono-1/2 cells and platelets after coronary bypass in cardiac patients. Thromb Haemost. 2017 May 11. doi: 10.1160/TH17-03-0184.

Wu LH, Chang SC, Fu TC, Huang CH, Wang JS*. High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep. 2017 Jun 23;7(1):4191.

Yeh TT , Hsieh YW, Wu CY, Wang JS, Chen CL. A preliminary investigation of the association of sleep with inflammation and oxidative stress biomarkers and functional outcomes after stroke rehabilitation. Sci Rep. 2017, Aug 17;7(1):8634.

Chen, K.H., Lin, J.L., Lin-Tan, D.T., Hsu, H.H., Hsu, C.W., Hsu, K.H., Yen, T.H. (2012) Effect of chelation therapy on progressive diabetic nephropathy in patients with type 2 diabetes and high-normal body lead burdens. Am J Kidney Dis., 60(4):530-8.

Venkitachalam, S., Chueh, F.Y., Yu, C.L. (2012) Nuclear localization of lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (Lmo2) gene. Biochem. Biophys. Res. Commun., 417(3):1058-1062.

Chueh, F.-Y. Yu, C.-L. (2012) Engagement of T-cell antigen receptor and CD4/CD8 co-receptors induces prolonged STAT activation through autocrine/paracrine stimulation in human primary T cells. Biochem. Biophys. Res. Commun., 426(2):242-246.

Hua M.Y., Lin Y.C., Tsai R.Y., Chen H.C. (2012) Water dispersible 1-one-butyric acid-functionalised multi-walled carbon nanotubes for enzyme immobilisation and glucose sensing. J. Mater. Chem., 22(6):256674

Ho HY, Cheng ML, Shiao MS, Chiu DT. (2013) Characterization of global metabolic responses of glucose-6-phosphate dehydrogenase-deficient hepatoma cells to diamide-induced oxidative stress. Free Radic Biol Med., 54:71-84.

Chen H.C., Tsai R.Y., Chen Y.H., Lee R.S., Hua M.Y. (2013) A colloidal suspension of nanostructured poly(N-butylbenzimidazole)-graphene sheets with high oxidase yield foranalytical glucose and choline detections. Analy. Chim. Acta, 792:1019

Chen H.C., Chen Y.H., Chen S.L., Chern Y.T., Tsai R.Y., Hua M.Y. (2013) Preparation of highly conjugated water-dispersible graphene- butyric acid for the enhancement of electron transfer within polyamic acid- benzoxazole: potential applications in electrochemical sensing. Biosen. & Bioelec., 46, 84–90.

Ho HY, Cheng ML, Chiu DT. (2014) Glucose-6-phosphate dehydrogenase – beyond the realm of red cell biology. Free Radic Res., 48(9):1028-48.

Chen, K.H., Hsu, H.H., Lee, C.C., Yen, T.H., Ko, Y.C., Yang, C.W., Hung, C.C. (2014) The AMPK Agonist AICAR Inhibits TGF-β1 Induced Activation of Kidney Myofibroblasts. PLoS One, 9(9):e106554.

Chueh, F.Y., Cronk, R.J., Alsuwaidan, A.N., Mallers, T.M., Jaiswal, M.K., Beaman, K.D., Yu, C.-L. (2014) Mouse LSTRA leukemia as a model of human natural killer T cell and highly aggressive lymphoid malignancies.  Leuk. Lymphoma, 55(3):706-708.

Chen, K.H., Chen, C.Y., Lee, C.C., Weng, C.M., Hung, C.C. (2014) Baseline hyponatremia does not predict two-year mortality in patients with chronic peritoneal dialysis. Ren Fail., 36(9):1371-5.

Cheng ML, Weng SF, Kuo CH, Ho HY. (2014) Enterovirus 71 induces mitochondrial reactive oxygen species generation that is required for efficient replication. PLoS One., 9(11):e113234.

Hung LM, Huang JP, Liao JM, Yang MH, Li DE, Day YJ & Huang SS. Insulin renders diabetic rats resistant to acute ischemic stroke by arresting nitric oxide reaction with superoxide to form peroxynitrite. Journal of Biomedical Science 21: 92, 2014.

Chang CC, Yang MH, Tung HC, Chang CY, TSAI YL, Huang JP, YEN TH & Hung LM. Resveratrol exhibits differential protective effects on fast- and slow-twitch muscles in streptozotocin-induced diabetic rats. Journal of Diabetes 6(1):60-7, 2014.

Huang SS, Lu YJ, Huang JP, Wu YT, Day YJ & Hung LM. The essential role of eNOS activation in insulin-mediated neuroprotection against ischemic stroke in diabetes. Journal of Vascular Surgery, 59:483-91, 2014.

Chen H.C., Qiu J.T., Yang F.L., Liu Y.C., Chen M.C., Tsai R.Y., Yang H.W., Lin C.Y., Lin C.C., Wu T.S., Xiao M.C., Tu Y.M., Ho C.H., Huang C.C., Lai C.S., Hua M.Y. (2014) Magnetic-composite-modified polycrystalline-silicon nanowire field-effect transistor for vascular endothelial growth factor detection and cancer diagnosis. Analy. Chem., 86(9):9443−50.

Wu YH, Chiu DT, Lin HR, Tang HY, Cheng ML, Ho HY. (2015) Glucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB Signaling. Viruses., 7(12):6689-706.

Vahedi, S., Chueh, F.Y., Dutta, S., Chandran, B., Yu, C.L. (2015) Nuclear lymphocyte-specific protein tyrosine kinase and its interaction with CR6-interacting factor 1 promote the survival of human leukemic T cells.  Oncol. Rep., 34(1):43-50.

Vahedi, S., Chueh, F.-Y., Chandran, B., Yu, C.L. (2015) Lymphocyte-specific protein tyrosine kinase (Lck) interacts with CR6-interacting factor 1 (CRIF1) in mitochondria to repress oxidative phosphorylation.  BMC Cancer, 15:551.

Chen H.C., Chen Y.T., Tsai R.Y., Chen M.C., Chen S.L., Xiao M.C., Chen C.L., Hua M.Y. (2015) A sensitive and selective magnetic graphene composite-modified polycrystalline-silicon nanowire field-effect transistor for bladder Cancer diagnosis. Biosen. Bioelect., 66:198−207.

Cheng ML, Chi LM, Wu PR, Ho HY. (2016) Dehydroepiandrosterone-induced changes in mitochondrial proteins contribute to phenotypic alterations in hepatoma cells. Biochem Pharmacol., 117:20-34.

Chen, K.H., Hsu, H.H., Yang, H.Y., Tian, Y.C., Ko, Y.C., Yang, C.W., Hung, C.C. (2016) Inhibition of spleen tyrosine kinase (syk) suppresses renal fibrosis through anti-inflammatory effects and down regulation of the MAPK-p38 pathway. Int J Biochem Cell Biol., 74:135-144.

Huang JP, Cheng ML, Wang CH, Shiao MS, Chen JK, Hung LM. High-fructose and high-fat feeding correspondingly lead to the development of lysoPC-associated apoptotic cardiomyopathy and adrenergic signaling-related cardiac hypertrophy. International Journal of Cardiology, 215:65-76, 2016.

Chang CC, Lin KY, Peng KY & Hung LM. Resveratrol exerts anti-obesity effects in high-fat diet obese mice and displays differential dosage effects on cytotoxicity, differentiation, and lipolysis in 3T3-L1 cells. Endocrine Journal 63(2):169-78, 2016.

Yang H.W., Tsai R.Y., Chen J.P., Ju S.P., Liao J.F., Wei K.C., Zou W.L., Hua M.Y. (2016) Fabrication of a nano-gold-dot array for rapid and sensitive detection of vascular endothelial growth factor in human serum. ACS Appl. Mater. & Interfaces, 8:3084552.

Chen SG, Cheng ML, Chen KH, Horng JT, Liu CC, Wang SM, Sakurai H, Leu YL, Wang SD, Ho HY. (2017) Antiviral activities of Schizonepeta tenuifolia Briq. against enterovirus 71 in vitro and in vivo. Sci Rep., 7(1):935.

Ho HY, Lin YT, Lin G, Wu PR, Cheng ML. (2017) Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation. Redox Biol., 12:916-928.

Chen SG, Leu YL, Cheng ML, Ting SC, Liu CC, Wang SD, Yang CH, Hung CY, Sakurai H, Chen KH, Ho HY. (2017) Anti-enterovirus 71 activities of Melissa officinalis extract and its biologically active constituent rosmarinic acid. Sci Rep. , 7(1):12264.

Huang JP, Cheng ML, Hung CY, Wang CH, Hsieh PS, Shiao MS, Chen JK, Li DE, Hung LM. Docosapentaenoic acid and Docosahexaenoic acid positively associate with insulin sensitivity in rats fed high-fat and high-fructose diets. Journal of Diabetes, 9(10):936-946, 2017.

CHEN FP , HUANG TS,  Fu TS, Sun CC, Chao AS, Tsai TL. Secular Trends in Incidence and Recurrence Rates for Hip Fracture: A Nationwide Population-Based Study. Osteoporos Int 2017;28:811-818.

Chen LW, Chen FP, Hsieh CW, Kuo SF, Chien RN. Analysis of the associations among Helicobacter pylori infection, adiponectin, leptin, and 10-year fracture risk using the fracture risk assessment tool: A cross-sectional community-based study. PLoS One. 2017;12(4):e0175365.

Lin YC, Huang TS, Wu JS, Cheung YC, Huang YH, Sung CM, Juan YH, Chen FP, Ni Mhuircheartaigh JM. Are bilateral decubitus views necessary in assessing for vertebral compression fractures using DXA vertebral fracture assessment? Osteoporos Int. 2017 Aug;28(8):2377-2382.

CHAO AS, CHEN FP (Correspondence), LIN YC, HUANG TS, FAN CM, YU YW. Application of the WHO Fracture Risk Assessment Tool (FRAX®) to Predict Need for DXA Scanning in Postmenopausal Women. Taiwan J Obstet Gynecol. 2015; 54:722-725.

Chen C N, Thompson LV. Interplay between aging and unloading on oxidative stress in fast-twitch muscles.J Gerontol A Biol Sci Med Sci. 2013 Jul;68(7):793-802.

Chen CN, Lin SY, Liao YH, et al. Late-onset caloric restriction alters skeletal muscle metabolism by modulating pyruvate metabolism.Am J Physiol Endocrinol Metab. 2015 Jun 1;308(11):E942-9.

Shyu YIL,* Chen MC, Liang J, Wu CC, Su JY. (2004). Predictors of functional recovery for hip fractured elders at 12 months following hospital discharge: A prospective study on a Taiwanese sample. Osteoporosis International, 15(6), 475-482.

Shyu YIL,* Lu JfR, Liang J. (2004). Evaluation of medical outcomes study short form-36 Taiwan version in assessing elderly patients with hip fracture. Osteoporosis International, 15(7), 575-582.

Shyu YIL,* Chen MC, Liang J, Lu JFR, Wu CC, Su JY. (2004). Changes in quality of life among elderly patients with hip fracture in Taiwan. Osteoporosis International, 15(2), 95-102.

Shyu YIL,* Chen MC, Lee HC. (2004). Caregiver’s needs as predictors of hospital readmission for the elderly in Taiwan. Social Science & Medicine, 58(7), 1395-1403

Shyu YIL,* Tang WR, Tsai WC, Liang J, Chen MC. (2006). Emotional support levels can predict physical functioning and health related quality of life among elderly Taiwanese with hip fractures. Osteoporosis International, 17(4), 501-506.

Shyu YIL,* Chen MC, Cheng HS, Deng HC, Liang J, Wu CC, Tsai WC. (2008). Severity of depression risk predicts health outcomes and recovery following surgery for hip-fractured elders. Osteoporosis International, 19(11), 1541-1547.

Shyu YIL,* Liang J, Wu CC, Su JY, Cheng HS, Chou SW, Chen MC, Yang CT, Tseng MY. (2010). Two-year effects of interdisciplinary intervention for hip fracture in older Taiwanese. Journal of the American Geriatrics Society, 58(6), 1081-1089.

Shyu YI L,* Liang J, Tseng MY, Li HJ, Wu CC, Cheng HS, Yang CT, Chou SW, Chen CY. (2013). Comprehensive care improves health outcomes among elderly Taiwanese patients with hip fracture. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 68(2), 188-197.

Huang LT, Wong AM, Chen CP, Chang WH, Cheng JW, Lin YR, Pei YC. (2013). Global motion percept mediated through integration of barber poles presented in bilateral visual hemifields. PLoS One, 8(8):e74032.

Liu, H.-Y., Tseng, M.-Y., Li, H.-J., Wu, C.-C., Cheng, H.-S., Yang, C.-T., Chou, S.-W., Chen, C.-Y., & Shyu, Y.-I. L.*(2014). Comprehensive care improves physical recovery of hip-fractured elderly Taiwanese patients with poor nutritional status. Journal of the American Medical Directors Association, 15(6), 416-422.

Wang CL, Shyu YIL,* Wang JY, Lu CH. (2017). Progressive compensatory symbiosis: Spouse caregiver experiences of caring for persons with dementia in Taiwan. Aging & Mental Health, 21(3), 241-252.

Shyu YIL, Tseng MY, Liang J,* Tsai WC, Wu CC, Cheng HS (2013). Interdisciplinary intervention decreases cognitive impairment for older Taiwanese with hip fracture: two-year follow-up. International Journal of Geriatric Psychiatry, 28:1222-1231.

Kuo LM, Huang HL, Hsu WC, Shyu YIL* (2014). Health-related quality of life and self-efficacy of managing behavior problems for family caregivers of vascular dementia and Alzheimer‘s disease patients. Dementia and Geriatric Cognitive Disorders, 38:310-320.

Wang HP, Liang J, Kuo LM, Shyu YIL* (2017). Trajectories of nutritional status and cognitive impairment among older Taiwanese with hip fracture. Journal of Nutrition Health & Aging, 21:38-45.

Kuo LM, Huang HL, Liang J, Kwok YT, Hsu WC, Su PL, Shyu, YIL* (2017). A randomised controlled trial of a home-based training programme to decrease depression in family caregivers of persons with dementia. Journal of Advanced Nursing, 73:585-598.

Lu C-S, Ng S-H, Weng Y-H, Cheng J-S, Lin W-Y, Wai Y-Y, Chen Y-L, Wang J-J*. Alterations of diffusion tensor MRI parameters in the brains of patients with Parkinson’s disease compared with normal brains: Possible diagnostic use. European Radiology. 2016;26(11), 3978-3988.

Lin S-H, Hsu W-C, Ng S-H, Cheng J-S, Khegai O, Huang C-C, Chen Y-L, Chen Y-C, Wang J-J*. Increased water diffusion in the parcellated cortical regions from the patients with amnestic mild cognitive impairment and Alzheimer's disease. Frontiers in Aging Neuroscience. 2017, 8.

Hsu KH, Tsui KH, Hsu LI, Chiou HY, & Chen CJ (2017). Dose-Response Relationship between Inorganic Arsenic Exposure and Lung Cancer among Arseniasis Residents with Low Methylation Capacity. Cancer Epidemiology Biomarkers & Prevention (In press.).

Hsu LI, Hsieh FI, Wang YH, Lai TS, Wu MM, Chen CJ, Chiou HY, Hsu KH. (2017). Arsenic Exposure from Drinking Water and the Incidence of CKD in Low to Moderate Exposed Areas of Taiwan: A 14-Year Prospective Study. American Journal of Kidney Diseases (In press.).

Lin TY, Chen CY, Tsao CY, Hsu KH (2017). The Association Between Personal Income and Aging: A Population-based 13-year Longitudinal Study. Archives of Gerontology and Geriatrics, 70, 76-83.

Yen AMF, Boucher BJ, Chiu SYH, Fann JCY, Chen SLS, Huang KC, Chen HH. (2016). Longer Duration and Earlier Age of Onset of Paternal Betel Chewing and Smoking Increase Metabolic Syndrome Risk in Human Offspring, Independently, in A Community-based Screening Program in Taiwan. Circulation, 134(5), 392-404.

Chiu YH, Wu SC, Tseng CD, Yen MF, Chen THH (2006). Progression of Pre-hypertension, Stage 1 and 2 Hypertension (JNC 7): A Population-based Study in Keelung, Taiwan (Keelung Community-based Integrated Screening No. 9). Journal of Hypertension, 24(5), 821-828.

Chiu SYH, Chen LS, Yen AMF, Chen HH (2011). Population-based Proband-oriented Pedigree Information System: Application to Hypertension With Population-based Screening Data (KCIS No. 25). Journal of the American Medical Informatics Association, 19(1), 102-110.

Lin JL, Lin-Tan DT, Hsu KH, Yu CC. Environmental Lead Exposure and Progression of Chronic Renal Diseases in Patients without Diabetes. New Engl J Med. 2003;348:277-286.

Hsu KH*, Shih CP, Liao PJ. Waist-to-thigh ratio is a predictor of internal organ cancers in humans: findings from a cohort study. Annals of Epidemiology. 2013;23(6):342-348.

Hung MJ, Hsu KH, Chang NC, Hung MY. Increased Numbers of Coronary Events in Winter and Spring Due to Coronary Artery Spasm: Effect of Age, Sex, Smoking, and Inflammation. J Am Coll Cardiol .2015; 65(18):2047-8.

Yang SC, Chung PJ, Ho CM, Kuo CY, Hung MF, Huang YT, Chang WY, Chang YW, Chan KH, Hwang TL*. Propofol Inhibits Superoxide Production, Elastase Release, and Chemotaxis in Formyl Peptide-Activated Human Neutrophils by Blocking Formyl Peptide Receptor 1. J Immunol. 2013 Jun 15;190(12):6511-9.

Chen CY, Liaw CC, Chen YH, Chang WY, Chung PJ, Hwang TL*. A novel immunomodulatory effect of ugonin U in human neutrophils via stimulation of phospholipase C. Free Radic Biol Med. 2014 Jul;72:222-31.

Lin CH, Aljuffali IA, Fang JY*. Lasers as an approach for promoting drug delivery via skin. Expert Opin Drug Deliv. 2014 Apr;11(4):599-614.

Tsai YF, Hwang TL*. Neutrophil elastase inhibitors: a patent review and potential applications for inflammatory lung diseases (2010 - 2014). Expert Opin Ther Pat. 2015 Oct;25(10):1145-58. Review.

Tsai YF, Yu HP, Chung PJ, Leu YL, Kuo LM, Chen CY, Hwang TL*. Osthol attenuates neutrophilic oxidative stress and hemorrhagic shock-induced lung injury via inhibition of phosphodiesterase 4. Free Radic Biol Med. 2015 Dec;89:387-400.

Aljuffali IA, Pan TL, Sung CT, Chang SH, Fang JY*. Anti-PDGF receptor β antibody-conjugated squarticles loaded with minoxidil for alopecia treatment by targeting hair follicles and dermal papilla cells. Nanomedicine. 2015 Aug;11(6):1321-30.

Fang CL, Wen CJ, Aljuffali IA, Sung CT, Huang CL, Fang JY*. Passive targeting of phosphatiosomes increases rolipram delivery to the lungs for treatment of acute lung injury: An animal study. J Control Release. 2015 Sep 10;213:69-78.

Aljuffali IA, Lin YK, Fang JY*. Noninvasive approach for enhancing small interfering RNA delivery percutaneously. Expert Opin Drug Deliv. 2016;13(2):265-80.

Aljuffali IA, Lin CF, Chen CH, Fang JY*. The codrug approach for facilitating drug delivery and bioactivity. Expert Opin Drug Deliv. 2016 Sep;13(9):1311-25.

Tsai YF, Yang SC, Hwang TL*. Formyl peptide receptor modulators: a patent review and potential applications for inflammatory diseases (2012-2015). Expert Opin Ther Pat. 2016 Aug 3:1-18. Review.

Chen CY, Tsai YF, Chang WY, Yang SC, Hwang TL*. Marine Natural Product Inhibitors of Neutrophil-Associated Inflammation. Mar Drugs. 2016 Jul 26;14(8). pii: E141. doi: 10.3390/md14080141. Review.

Chen CY, Yang CH, Tsai YF, Liaw CC, Chang WY, Hwang TL*. Ugonin U stimulates NLRP3 inflammasome activation and enhances inflammasome-mediated pathogen clearance. Redox Biol. 2016 Dec 18;11:263-74.

Lin MH, Hung CF, Aljuffali IA, Sung CT, Huang CT, Fang JY*. Cationic amphiphile in phospholipid bilayer or oil-water interface of nanocarriers affects planktonic and biofilm bacteria killing. Nanomedicine. 2017 Feb;13(2):353-61.

Gaber M, Medhat W, Hany M, Saher N, Fang JY*, Elzoghby A*. Protein-lipid nanohybrids as emerging platforms for drug and gene delivery: Challenges and outcomes. J Control Release. 2017 May 28;254:75-91.

Hsu CY, Sung CT, Aljuffali IA, Chen CH, Hu KY, Fang JY*. Intravenous anti-MRSA phosphatiosomes mediate enhanced affinity to pulmonary surfactants for effective treatment of infectious pneumonia. Nanomedicine. 2017 Nov 8. pii: S1549-9634(17)30186-7. doi: 10.1016/j.nano.2017.10.006. [Epub ahead of print].

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Chen, S-W., Liaw, J-W., Chang, Y, Chan, H-L., Chiu, L-Y. (2015): A cycling movement based system for real-time muscle fatigue and cardiac stress monitoring and analysis. PLoS ONE, 10(6):e0130798. (SCI, IF=3.234, MULTIDISCIPLINARY SCIENCES: 8/56)

Chang, Y., Chou, C-C., Huang, W-T., Lu, C-S., Wong, A-M., & Hsu, M. (2015) Cycling regimen induces spinal circuitry plasticity and improves leg muscle coordination in individuals with spinocerebellar ataxia. Archives of Physical Medicine and Rehabilitation, 96(6):1006-13. (SCI, IF=2.565, Rehabilitation: 7/64)

Fan, Y-T., Wu, C-Y.†, Liu, H-L., Lin, K-C., Wai, Y-Y., & Chen, Y-L. (2015). Neuroplastic changes in resting-state functional connectivity after stroke rehabilitation. Frontiers in Human Neuroscience, 9: 546, 1-12. (SCI, IF=3.209, PSYCHOLOGY: 17/77)

Chen, H-L., Lin, K-C., Liing, R-J., Wu, C-Y.*, & Chen, C-L. (2015). Kinematic measures of arm-trunk movements during unilateral and bilateral reaching predict clinically important change in perceived arm use in daily activities after intensive stroke rehabilitation. Journal of NeuroEngineering and Rehabilitation, 12: 84, 1-10. (SCI, IF= 3.516, REHABILITATION: 3/65)

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Huang, W-P, Wang, C-C., Hung, J-H., Chien, K-C., Liu, W-Y., Cheng, C-H., Ng, H-H., & Lin Y-H. (2015)Joystick-Controlled Video Console Game Practices for Power Wheelchairs Indoor Driving Skills. Journal of Physical Therapy Science, 27(2), 495-498. (SCI, IF=0.392, REHABILITATION: 61/64)

Hsieh, Y-W., Lin, K-C., Horng, Y-S., Wu, C-Y.*, Wu, D-J., & Ku, F-L. (2014). Sequential combination of robot-assisted therapy and constraint-induced therapy in stroke rehabilitation: A randomized controlled trial. Journal of Neurology, 261(5), 1037-1045. (SCI, IF=3.389, CLINICAL NEUROLOGY: 59/194)

Hsieh, Y-W., Lin, K-C., Korivi, M., Lee, T-H., Wu, C-Y.*, & Wu, K-Y. (2014). The reliability and predictive ability of a biomarker of oxidative DNA damage on functional outcomes after stroke rehabilitation. International Journal of Molecular Sciences, 15(4), 6504-6516. (SCI, IF=3.226, CHEMISTRY, MULTIDISCIPLINARY: 54/166)

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Chen, S-W., Liaw, J-W., Chan, H-L., Chang, Y., & Ku, C-H. (2014) A real-time fatigue monitoring and analysis system for lower extremity muscles with cycling movement. Sensors, 14:12410-24. (SCI, IF=2.245, INSTRUMENTS & INSTRUMENTATION: 10/56)

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Chang, Y-C., Lin, C-C., Lin, P-H., Chen, C-C., Lee, R-G., Huang, J-S., & Tsai, T-H. (2013) eFurniture for home-based frailty detection using artificial neural networks and wireless sensors. Medical Engineering & Physics, 35(2), 263-268. (SCI, IF=1.819, ENGINEERING, BIOMEDICAL: 46/77)

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Chang, Y., Chou, C-C., Chan, H-L., Hsu, M., Yeh, M-Y., Fang, C-Y., Chuang, Y-F., Wei, S-H., & Lien, H-Y. (2012) Increases of quadriceps inter-muscular cross-correlation and coherence during exhausting stepping exercise. Sensors, 12 :16353-67. (SCI, IF=2.245, INSTRUMENTS & INSTRUMENTATION: 10/56)

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Hsieh, Y-W., Wu, C-Y., & Lin, K-C. (2009). Response to letter by Sivan regarding interpreting effect size to estimate responsiveness of outcome measures. Stroke, 40, e710-e711. (SCI, IF=6.032, CLINICAL NEUROLOGY: 16/194)

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Lu, C.F., Hsu, C.L., and Lin, H.Y., Provably Convertible Multi-Authenticated Encryption Scheme for Generalized Group Communications, Information Sciences, Vol. 199, No. 15, September, 2012, pp. 154-166. <SCI: 3.643 (2012), 6/132 in COMPUTER SCIENCE, INFORMATION SYSTEMS >

Hsu, C.L., Tseng, K.C., and Chuang, Y.H. , A Secure IRB System for Assisting the Development of Intelligent Medical Devices, Expert Systems With Applications, Vol. 39, No. 15, November, 2012, pp. 12512-12521. <SCI:2.203 (2011), 22/111 in COMPUTER SCIENCE, ARTIFICIAL INTELLIGENCE, 41/245 in ENGINEERING, ELECTRICAL & ELECTRONIC, 5/77 in OPERATIONS RESEARCH & MANAGEMENT SCIENCE>

Tseng, K.C., Wong, A.M.K., Hsu, C.L., Tsai, T.H., Han, C.M., and Lee, M.R., The iFit: An Integrated Physical Fitness Testing System to Evaluate the Degree of Physical Fitness of the Elderly, IEEE Transactions on Biomedical Engineering, August, 2012. <SCI: 2.278 (2011),22/72 in ENGINEERING, BIOMEDICAL>

Hsu, C.L., Lee, M.R., and Su, C.H., “The Role of Privacy Protection in Healthcare Information Systems Adoption,” Journal of Medical Systems, Vol. 37:9966, No. 5, P. 1-12, October 2013. <SCI: 1.372 (2013), 14/25 in MEDICAL INFORMATICS>

Tseng, K.C., Hsu, C.L., and Chuang, Y.H., “Designing an Intelligent Health Monitoring System and Exploring User Acceptance for the Elderly,” Journal of Medical Systems, Vol. 37:9967, No. 6, P. 1-18, September 2013. <SCI: 1.372 (2013), 54/86 in MEDICAL INFORMATICS>

Hsu, C.L., and Lin, Y.L., “Improved Migration for Mobile Computing in Distributed Networks,” Computer Standards & Interfaces, Vol. 36, No. 3, pp. 577-584, March 2014. < SCI: 1.177(2013), 38/105 in COMPUTER SCIENCE, SOFTWARE ENGINEERING >

Lin, C.H., Lin, I.C., Roan, J.S., Huang, W.M., and Hsu, C.L., “Explaining physicians' attitude to a new healthcare information technology: adoption and resistance perspectives,” International Journal of Medical Informatics (Under Reviewer) <SSCI: 2.716 (2013), 13/135 in INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS >

Hsu, C.L. and Lin, H.Y. “Covertible Authenticated Encryption Scheme with Hierarchical Access Control,” Applied Mathematics & Information Sciences, Vol. 8, No.5   pp.1239-1246, May 2014..<SCI: 1.232 (2013), 53/251 in MATHEMATICS, APPLIED>

Tsai, T.H., Wong, A.M.K., Hsu, C.L., Tseng, K.C.*, “Research on a Community-based Platform for Promoting Health and Physical Fitness in the Elderly Community,” PLoS ONE, Vol. 8, No. 2, February, 2013. <SCI: 3.534 (2013), 8/55 in MULTIDISCIPLINSRY SCIENCES>

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Chen TL, Yang HC, Hung CY, Ou MH, Pan YY, Cheng ML, Stern A, Lo SJ, Chiu DT. (2017) Impaired embryonic development in glucose-6-phosphate dehydrogenase-deficient Caenorhabditis elegans due to abnormal redox homeostasis induced activation of calcium-independent phospholipase and alteration of glycerophospholipid metabolism. Cell Death and Disease 8(1):e2545. (SCI IF=5.965 , CELL BIOLOGY   39/190)

Ho HY, Lin YT, Lin G, Wu PR, Cheng ML. (2017) Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation. Redox Biology 12:916-928. (SCI IF=6.337 , BIOCHEMISTRY & MOLECULAR BIOLOGY  34/290)

Lin YH, Wu MH, Huang YH, Yeh CT, Cheng ML, Chi HC, Tsai CY, Chung IH, Chen CY, Lin KH. (2017) Taurine upregulated gene 1 functions as a master regulator to coordinate glycolysis and metastasis in hepatocellular carcinoma. (2017) Hepatology (SCI IF=13.246 , GASTROENTEROLOGY & HEPATOLOGY   4/79)

Cheng ML, Chi LM, Wu PR, Ho HY (2016) Dehydroepiandrosterone-induced changes in mitochondrial proteins contribute to phenotypic alterations in hepatoma cells. Biochemical Pharmacology 117:20–34 (SCI IF=5.091, PHARMACOLOGY &PHARMACY 18/255)

Chiu CY, Lin G, Cheng ML, Chiang MH, Tsai MH, Lai SH, Wong KS, Hsieh SY. (2016) Metabolomic Profiling of Infectious Parapneumonic Effusions Reveals Biomarkers for Guiding Management of Children with Streptococcus pneumoniae Pneumonia. Scientific Reports 6:24930 (SCI IF=5.228, MULTIDISCIPLINARY SCIENCES 7/63)

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Chan S-C, Cheng N-M, Hsieh C-H, Ng S-H, Lin C-Y, Yen T-C, Hsu C-L, Wan H-M, Liao C-T, Chang K-P, Wang J-J*. Multiparametric imaging using 18F-FDG PET/CT heterogeneity parameters and functional MRI techniques: prognostic significance in patients with primary advanced oropharyngeal or hypopharyngeal squamous cell carcinoma treated with chemoradiotherapy. Oncotarget. 2017;5.

Lin S-H, Hsu W-C, Ng S-H, Cheng J-S, Khegai O, Huang C-C, Chen Y-L, Chen Y-C, Wang J-J*. Increased Water Diffusion in the Parcellated Cortical Regions from the Patients with Amnestic Mild Cognitive Impairment and Alzheimer's Disease. Frontiers in Aging Neuroscience. 2017;8.

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Wai Y-Y, Hsu W-C, Fung H-C, Lee J-D, Chan H-L, Tsai M-L, Lin Y-C, Wu Y-R, Ying L, Wang J-J*. Tract-based spatial statistics: application to mild cognitive impairment. BioMed research international. 2014;2014.

Ng SH, Hsu WC, Wai YY, Lee JD, Chan HL, Chen YL, Fung HC, Wu YR, Tsai ML, Wang JJ*. Sex dimorphism of cortical water diffusion in normal aging measured by magnetic resonance imaging. Frontiers in aging neuroscience 2013; vol 5: P 71.

Wai Y-Y, Wang J-J*, Weng Y-H, Lin W-Y, Ma H-K, Ng S-H, Wan Y-L, Wang C-H. Cortical involvement in a gait-related imagery task: comparison between Parkinson’s disease and normal aging. Parkinsonism & related disorders. 2012;18(5):537-42.

Chang CC, Chang WN, Lui CC, Huang SH, Lee CC, Chen C, Wang JJ*. Clinical significance of the pallidoreticular pathway in patients with carbon monoxide intoxication. Brain 2011; vol 134(12):                      P 3632-3646.


Wang JJ, Lin WY, Lu CS, Weng YH, Ng SH, Wang CH, Liu HL, Hsieh RH, Wan YL, Wai YY*. Parkinson disease: diagnostic utility of diffusion kurtosis imaging. Radiology 2011; vol 261(1): P                 210-217.